Rule in Eire ignited rebellion (5)
I believe the answer is:
reign
'rule' is the definition.
(reign is a kind of rule)
'in eire ignited rebellion' is the wordplay.
'in' indicates the answer is hidden within the clue.
'REIGN' is hidden within 'eire ignited rebellion'.
(Other definitions for reign that I've seen before include "Hegemony" , "Wield the sceptre" , "Sit on a throne" , "Time on throne" , "Period of a monarchy" .)