Run aboard huge vessel (4)
I believe the answer is:
brig
'vessel' is the definition.
(brig is a kind of vessel)
'run aboard huge' is the wordplay.
'run' becomes 'r' (cricket abbreviation).
'aboard' indicates putting letters inside.
'huge' becomes 'big' (similar in meaning).
'r' placed into 'big' is 'BRIG'.
(Other definitions for brig that I've seen before include "Two-masted square-rigged vessel" , "'Two-masted,square-rigged ship (4)'" , "staff officer briefly used" , "Two-masted ship; gaol" , "Two-masted square-rigger" .)