Run away to wed an Eastern European returning to the East
I believe the answer is:
elope
'run away to wed' is the definition.
(I've seen this before)
'an eastern european returning to the east' is the wordplay.
'an eastern european' becomes 'Pole'.
'returning' says the letters should be written backwards.
'to the east' becomes 'e' (synonyms).
'pole' reversed gives 'elop'.
'elop'+'e'='ELOPE'
(Other definitions for elope that I've seen before include "Run away to Gretna Green?" , "Run away with one's beloved" , "Run away together" , "Abscond for amorous purposes" , "escape" .)