Run through beginning of recitative in musical work (6)
I believe the answer is:
pierce
'run through' is the definition.
(I've seen this before)
'beginning of recitative in musical work' is the wordplay.
'beginning of' suggests taking the first letters.
'in' means one lot of letters goes inside another.
'musical work' becomes 'piece' (synonyms).
The initial letter of 'recitative' is 'r'.
'r' inserted into 'piece' is 'PIERCE'.
(Other definitions for pierce that I've seen before include "Cavalry sword" , "pink" , "go through" , "Make hole in, penetrate" , "- Brosnan; (to) hole" .)