Run-in with leading girl band (4)
I believe the answer is:
ring
'band' is the definition.
(synonyms)
'run-in with leading girl' is the wordplay.
'run' becomes 'r' (cricket abbreviation).
'with' means one lot of letters go next to another.
'leading' indicates taking the first letters.
The first letter of 'girl' is 'g'.
'r'+'in'+'g'='RING'
(Other definitions for ring that I've seen before include "Circus space; surround" , "token of love" , "Telephone - as bells do" , "13's story of a 17" , "sound as a bell" .)