Running nude in street, not giving a hoot (12)
I believe the answer is:
uninterested
'not giving a hoot' is the definition.
I can't tell whether this definition defines the answer.
'running nude in street' is the wordplay.
'running' is an anagram indicator (the letters run around to different places).
'nude'+'in'+'street'='nudeinstreet'
'nudeinstreet' with letters rearranged gives 'UNINTERESTED'.
Can you help me to learn more?
(Other definitions for uninterested that I've seen before include "indifferent" , "Bored" , "Apathetic" , "Not concerned" .)