Runs away with the last tender (5)
I believe the answer is:
nurse
'tender' is the definition.
(someone who tends to patients)
'runs away with the last' is the wordplay.
'away with' indicates anagramming the letters (letters move away from their original places).
'last' indicates one should take the final letters.
The final letter of 'the' is 'e'.
'runs' mixed up with 'e' gives 'NURSE'.
(Other definitions for nurse that I've seen before include "Professional carer" , "Care for the sick" , "Child minder" , "dogfish or > worker bee" , "Qualified carer" .)