Runs out of air? Oh dear! (9)
I believe the answer is:
diarrhoea
'runs' is the definition.
(diarrhoea is informally called 'the runs')
'out of air? oh dear' is the wordplay.
'out of' is an anagram indicator.
'air'+'oh'+'dear'='airohdear'
'airohdear' anagrammed gives 'DIARRHOEA'.
I've seen this clue in The Guardian.
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