Rush through a life's work (6)
I believe the answer is:
career
I believe this is a double definition.
'rush' is the first definition.
(career can mean to run or move out of control)
'a life's work' is the second definition.
(someone's work or profession)
'through' is the link.
(Other definitions for career that I've seen before include "Life (in terms of work etc)" , "Run wildly" , "Long-term occupation" , "someone in profession" , "Occupation through time" .)