Sad Scot no ladies fancy (12)
I believe the answer is:
disconsolate
'sad' is the definition.
(I've seen this before)
'scot no ladies fancy' is the wordplay.
'fancy' indicates an anagram.
'scot'+'no'+'ladies'='scotnoladies'
'scotnoladies' with letters rearranged gives 'DISCONSOLATE'.
(Other definitions for disconsolate that I've seen before include "Melancholy" , "Unhappy and unable to be comforted" , "Unhappy and impossible to comfort" , "Sad; beyond comfort" , "Low in spirits" .)