Saddles rub with ends misshapen (7)
I believe the answer is:
burdens
'saddles' is the definition.
('burden' can be a synonym of 'saddle')
'rub with ends misshapen' is the wordplay.
'with' is a charade indicator (letters next to each other).
'misshapen' is an anagram indicator.
'rub' after 'ends' is 'endsrub'.
'endsrub' is an anagram of 'BURDENS'.
(Another definition for burdens that I've seen is " Heavy loads".)
I've seen this clue in The Sun.
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