Sad-looking whore regularly ignored? Get away! (9)
I believe the answer is:
woebegone
'sad-looking' is the definition.
(woebegone means looking miserable)
'whore regularly ignored? get away' is the wordplay.
'regularly ignored?' indicates alternate letters (letters removed at regular intervals).
'get away' becomes 'begone' (command to be gone).
The alternating letters of 'whore' are 'woe'.
'woe'+'begone'='WOEBEGONE'
(Other definitions for woebegone that I've seen before include "Unhappy" , "Sorry" , "forlorn state" , "Sad, miserable" , "Dismal-looking" .)