Sake? This can make you most unsteady! (8)
I believe the answer is:
shakiest
'most unsteady' is the definition.
'sake? this can make you' is the wordplay.
'can make you' indicates anagramming the letters.
'sake'+'this'='sakethis'
'sakethis' anagrammed gives 'SHAKIEST'.
(Other definitions for shakiest that I've seen before include "Least stable" , "most suspect" .)
I've seen this clue in The Times.
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