Sample different spice, fellows (8)
I believe the answer is:
specimen
'sample' is the definition.
(specimen is a kind of sample)
'different spice fellows' is the wordplay.
'different' indicates an anagram.
'fellows' becomes 'men' (I've seen this before).
'spice' anagrammed gives 'speci'.
'speci'+'men'='SPECIMEN'
(Other definitions for specimen that I've seen before include "Exemplar" , "blood sample" , "Test sample" , "Example for the collector or scientist" , "Something serving as an example" .)