Sample sweet extremities at meeting (5)
I believe the answer is:
tryst
'meeting' is the definition.
(tryst is a kind of meeting)
'sample sweet extremities' is the wordplay.
'sample' becomes 'try' (synonyms).
'extremities' suggests removing the centre.
'sweet' with its centre taken out is 'st'.
'try'+'st'='TRYST'
'at' acts as a link.
(Other definitions for tryst that I've seen before include "private meeting" , "meeting with another person" , "Romantic assignation" , "Pre-arranged (secret) meeting" , "meeting-place" .)