Satire spoke perhaps about sick hospital drama (8)
I believe the answer is:
raillery
'satire' is the definition.
(I have seen 'Playful satire' mean 'raillery' so perhaps 'satire' could also mean 'raillery')
'spoke perhaps about sick hospital drama' is the wordplay.
'spoke perhaps' becomes 'ray' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'about' indicates putting letters inside.
'sick' becomes 'ill' (similar in meaning).
'hospital drama' becomes 'er'.
'ill'+'er'='iller'
'ray' placed around 'iller' is 'RAILLERY'.
Can you help me to learn more?
(Other definitions for raillery that I've seen before include "(Example of) banter" , "Playful satire" , "Banter, back-chat" , "Light teasing repartee" , "Badinage" .)