Satisfied about unfortunate grain (6)
I believe the answer is:
millet
'grain' is the definition.
(millet is a kind of grain)
'satisfied about unfortunate' is the wordplay.
'satisfied' becomes 'met' ('meet' can be a synonym of 'satisfy').
'about' is an insertion indicator.
'unfortunate' becomes 'ill' ('ill' can be similar in meaning to 'unfortunate').
'met' going around 'ill' is 'MILLET'.
(Other definitions for millet that I've seen before include "Cereal grass used for flour" , "Budgie food" , "Food grain" , "Type of cereal" , "Type of grain" .)