Satisfy some people with ease (6)
I believe the answer is:
please
'satisfy' is the definition.
(pleasing is a kind of satisfying)
'some people with ease' is the wordplay.
'some people with' becomes 'pl' (I can't justify this - if you can you should believe this answer much more).
'pl'+'ease'='PLEASE'
Can you help me to learn more?
(Other definitions for please that I've seen before include "Entertain" , "Be good enough to" , "Make glad, being asleep" , "Gratify, make contented" , "See 10 Across" .)