Save Earl and Charlie taken in by drug taker giving everything up (6)
I believe the answer is:
rescue
'save' is the definition.
(rescuing is a kind of saving)
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for rescue that I've seen before include "Save from danger or distress" , "Salvage" , "liberation" , "Set free from harm and evil" , "delivery" .)