Score confused with a gross (6)
I believe the answer is:
coarse
'gross' is the definition.
('coarse' can be a synonym of 'gross')
'score confused with a' is the wordplay.
'confused with' indicates anagramming the letters.
'score' with its letters anagrammed with 'a' can make 'COARSE'.
(Other definitions for coarse that I've seen before include "Vulgar - unrefined" , "Rough-hewn" , "Boorish" , "needing refinement" , "gross" .)