Scoundrel with gag (6)
I believe the answer is:
wretch
'scoundrel' is the definition.
(thesaurus)
'with gag' is the wordplay.
'with' becomes 'w' (abbreviation).
'gag' becomes 'retch' (I've seen this before).
'w'+'retch'='WRETCH'
(Other definitions for wretch that I've seen before include "Someone to be pitied" , "Scoundrel" , "Unfortunate, miserable person" , "Poor, pitiable person" , "A pitiful, unfortunate person" .)