Screwed up to make a face (4)
I believe the answer is:
pout
'make a face' is the definition.
(pouting is a kind of making a face)
'screwed up to' is the wordplay.
'screwed' indicates an anagram.
'up'+'to'='upto'
'upto' is an anagram of 'POUT'.
(Other definitions for pout that I've seen before include "shows disappointed face" , "Push out one's lips" , "Look sullen" , "Express sulks with lips" , "Push lips forward in sulky expression" .)