Search female? Anger about that (5)
I believe the answer is:
rifle
'search' is the definition.
(I know that rifle is a more specific form of the action search)
'female? anger about that' is the wordplay.
'female?' becomes 'f' (abbreviation).
'anger' becomes 'rile' (rile can mean to annoy or anger).
'about that' indicates putting letters inside.
'f' inserted within 'rile' is 'RIFLE'.
(Other definitions for rifle that I've seen before include "Long-barrelled gun" , "Ransack - firearm" , "An arm" , "Flier (anag.)" , "Root" .)