Second effeminate scoundrel (5)
I believe the answer is:
scamp
'scoundrel' is the definition.
(I've seen this before)
'second effeminate' is the wordplay.
'second' becomes 's' (common abbreviation).
'effeminate' becomes 'camp' (I've seen this before).
's'+'camp'='SCAMP'
(Other definitions for scamp that I've seen before include "Scallywag" , "Scoundrel" , "pickle" , "Impish youngster" , "Impish child" .)