Crossword Genius

___ Secretary (5)

Ross

I believe the answer is:

madam

(Other definitions for madam that I've seen before include "Polite form of address for a woman" , "Palindrome used in speaking politely to a woman" , "Conceited girl (colloq.)" , "Leader of House of Congress" , "'Call Me ---' (I. Berlin)" .)

I've seen this clue in The New York Times.
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