Section of coursework not typically extremely difficult (6)
I believe the answer is:
knotty
'extremely difficult' is the definition.
(I've seen this before)
'section of coursework not typically' is the wordplay.
'section of' indicates a hidden word.
'KNOTTY' can be found hidden inside 'coursework not typically'.
(Other definitions for knotty that I've seen before include "puzzling" , "Tangled - snarled" , "Very difficult - complex" , "Awkward" , "Full of tangles; extremely intricate" .)