Seek a lift from drug, having desire (5)
I believe the answer is:
hitch
'seek a lift' is the definition.
(hitch-hiking)
'drug having desire' is the wordplay.
'drug' becomes 'h' (H is an example**).
'having' is a charade indicator (letters next to each other).
'desire' becomes 'itch' (itch is a kind of desire).
'h'+'itch'='HITCH'
'from' is the link.
(Other definitions for hitch that I've seen before include "knot" , "Snag - free ride" , "Snag, drawback" , "Make fast" , "Small problem" .)