Seize cutting-edge file (5)
I believe the answer is:
grasp
'seize' is the definition.
(I've seen this before)
'cutting-edge file' is the wordplay.
'cutting-edge' becomes 'g' (I can't justify this - if you can you should give a lot more credence to this answer).
'file' becomes 'rasp' (rasp is a kind of file).
'g'+'rasp'='GRASP'
Can you help me to learn more?
(Other definitions for grasp that I've seen before include "Support; rugby player" , "Seize firmly - or understand (5)" , "Firmly grip" , "Hold - understanding" , "Take firm hold" .)