Select church welcomes Soho drunk (6)
I believe the answer is:
choose
'select' is the definition.
(I know that select can be written as choose)
'church welcomes soho drunk' is the wordplay.
'church' becomes 'CE' (abbreviation for Church of England).
'welcomes' is an insertion indicator (in sense of 'invites in').
'drunk' is an anagram indicator.
'soho' with letters rearranged gives 'hoos'.
'ce' placed around 'hoos' is 'CHOOSE'.
(Other definitions for choose that I've seen before include "Think fit" , "Select, opt for" , "Elect" , "Make a selection" , "Pick, select." .)