Self-restraint sent most of cabinet mad (10)
I believe the answer is:
abstinence
'self-restraint' is the definition.
(thesaurus)
'sent most of cabinet mad' is the wordplay.
'most of' means to remove the last letter.
'mad' is an anagram indicator.
'cabinet' with its final letter taken away is 'cabine'.
'sent'+'cabine'='sentcabine'
'sentcabine' with letters rearranged gives 'ABSTINENCE'.
(Other definitions for abstinence that I've seen before include "Practice of refraining (from alcohol)" , "giving it up" , "Going without" , "Staying away from" , "Temperance" .)