Sense foul play following wife's misery (10)
I believe the answer is:
woefulness
'misery' is the definition.
(I know that misery can be written as woefulness)
'sense foul play following wife's' is the wordplay.
'play' is an anagram indicator.
'following' means one lot of letters go next to another.
'wife' becomes 'w'.
'sense'+'foul'='sensefoul'
'sensefoul' anagrammed gives 'oefulness'.
'oefulness' put after 'w' is 'WOEFULNESS'.
(Another definition for woefulness that I've seen is " Deplorable".)
I've seen this clue in The Independent.
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