Sent on prescribed course and heavily defeated (6)
I believe the answer is:
routed
I believe this is a double definition.
'sent on prescribed course' is the first definition.
(directed along a particular route)
'heavily defeated' is the second definition.
(to rout is to comprehensively defeat)
'and' is the link.
(Other definitions for routed that I've seen before include "Put to flight or sent a certain way" , "Put to flight or directed" , "Forced to leave" , "Vanquished" , "Sent on a particular course" .)