Serious disloyalty from maverick senator (7)
I believe the answer is:
treason
'serious disloyalty' is the definition.
'treason' can be an answer for 'disloyalty' (treason is a kind of disloyalty). I am unsure of the 'serious' bit.
'maverick senator' is the wordplay.
'maverick' indicates anagramming the letters.
'senator' with letters rearranged gives 'TREASON'.
'from' acts as a link.
Can you help me to learn more?
(Other definitions for treason that I've seen before include "Lese-majesty" , "Perfidy" , "Betrayal (of one's country)" , "Crime of national betrayal" , "Betrayal of one's nation" .)