Set a puzzle full of holes (7)
I believe the answer is:
riddled
I believe this clue is a double definition.
'set a puzzle' is the first definition.
'full of holes' is the second definition.
(Other definitions for riddled that I've seen before include "Spread throughout" , "Pierced with many holes as by tommygun" , "didn't talk plainly" , "spoken obscurely" , "screened" .)