Set upon endless path with love — sweet! (6)
I believe the answer is:
gelato
'sweet' is the definition.
(gelato is a type of dessert or sweet)
'set upon endless path with love' is the wordplay.
'set' becomes 'gel' (I've seen this before).
'upon' says to put letters next to each other.
'endless' says to take the centre.
'with' means one lot of letters go next to another.
'love' becomes 'o' (In tennis, 'love' means 'zero').
The central letters of 'path' are 'at'.
'gel'+'at'+'o'='GELATO'
(Other definitions for gelato that I've seen before include "treat in Milan?" , "Italian-style ice cream" , "Frozen food" , "Italian ice cream" .)