Sets about bizarre beings (6)
I believe the answer is:
begins
'sets about' is the definition.
('begin' can be a synonym of 'set about')
'bizarre beings' is the wordplay.
'bizarre' is an anagram indicator.
'beings' anagrammed gives 'BEGINS'.
(Other definitions for begins that I've seen before include "Starts" , "Makes a start" , "Commences" .)