Shakespeare made a laughing matter of them (6)
I believe the answer is:
errors
'shakespeare made a laughing' is the definition.
I can't judge whether this definition defines the answer.
'matter of them' is the wordplay.
I cannot really understand how this works, but
'matter' could be 'er' (Er is an example) and 'er' is found within the answer.
'of' could be 'o' and 'o' is located in the answer.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for errors that I've seen before include "Mistakes and inaccuracies" , "Subject of Shakespearean comedy" , "Faults" , "Blunders, slips" , "Gaffes" .)