Shame about dire upset (9)
I believe the answer is:
disrepute
'shame' is the definition.
(thesaurus)
'about dire upset' is the wordplay.
'about' is an anagram indicator.
'dire'+'upset'='direupset'
'direupset' with letters rearranged gives 'DISREPUTE'.
(Other definitions for disrepute that I've seen before include "Ignominy" , "get a bad name" , "State of being held in low public esteem" , "Ill fame" .)