Sharp, putting a group of detectives in charge (6)
I believe the answer is:
acidic
'sharp' is the definition.
(I've seen this before)
'a group of detectives in charge' is the wordplay.
'group of detectives' becomes 'CID' (Criminal Investigation Department).
'in charge' becomes 'ic' (abbreviation for 'in charge').
'a'+'cid'+'ic'='ACIDIC'
'putting' acts as a link.
(Other definitions for acidic that I've seen before include "Sarcastic or sour" , "Unpleasant" , "Tasting sharp or sour" , "Sharp-tasting, sour" , "Like vinegar" .)