Shattered relic by opening chamber (9)
I believe the answer is:
ventricle
'chamber' is the definition.
(ventricle is a kind of chamber)
'shattered relic by opening' is the wordplay.
'shattered' indicates an anagram.
'by' means one lot of letters go next to another.
'opening' becomes 'vent' (vent is a kind of opening**).
'relic' anagrammed gives 'ricle'.
'ricle' put after 'vent' is 'VENTRICLE'.
(Other definitions for ventricle that I've seen before include "Chamber in organ of body - the heart has two" , "Heart cavity that pumps blood to arteries" , "One of four heart chambers" , "bloody pump!" .)