She gives Rosalie heart (3)
I believe the answer is:
sal
'she' is the definition.
'rosalie heart' is the wordplay.
'heart' says to take the centre.
The central letters of 'rosalie' are 'SAL'.
'gives' is the link.
(Other definitions for sal that I've seen before include "girl?" , "Sarah (dim.)" , "- - volatile" .)