She makes a hit with Edward (5)
I believe the answer is:
edith
'she' is the definition.
(I've seen this before)
'makes a hit with edward' is the wordplay.
'makes' is an anagram indicator.
'with' means one lot of letters go next to another.
'edward' becomes 'Ed' (short for Edward).
'hit' with letters rearranged gives 'ith'.
'ith' after 'ed' is 'EDITH'.
(Other definitions for edith that I've seen before include "Cavell, Piaf or Wharton" , "girl" , "Eg Cavell" , "Dame ----- Evans (1888-1976), stage and screen actress" , "- Cavell, WW 1 heroine" .)