She seductively caused a man to lose his head (6)
I believe the answer is:
salome
'she' is the definition.
'seductively caused a man to lose his head' is the wordplay.
I cannot quite see how this works, but
'a' is present in the answer.
'man' could be 'm' and 'm' is present in the answer.
an anagram of 'lose' is 'sloe' which is present in the remaining letters.
This accounts for all the letters.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for salome that I've seen before include "Her dancing pleased Herod" , "She danced famously for Herod" , "revealing play" , "13 dn for Herod" , "She danced for the head of John the Baptist" .)