She will shortly be a nut case (5)
I believe the answer is:
shell
'a nut case' is the definition.
'shell' can be an answer for 'case' (synonyms). I am not certain of the 'a nut' bit.
'she will shortly' is the wordplay.
'she' becomes 'shel' ().
'shortly' suggests the final letters.
The final letter of 'will' is 'l'.
'shel'+'l'='SHELL'
'be' acts as a link.
Can you help me to learn more?
(Other definitions for shell that I've seen before include "Protective outer case" , "Carapace or explosive missile" , "See 18" , "Protective outer casing" , "Walls of gutted building" .)