Shed, throw off (4)
I believe the answer is:
cast
I believe this clue is a double definition.
'shed' is the first definition.
(shed can mean to discard or cast off)
'throw off' is the second definition.
(I know that throw off can be written as cast)
(Other definitions for cast that I've seen before include "Mould; actors in a play" , "Play's actors" , "The acting complement of a play" , "Set of performers" , "Discard; mould" .)