She's from Indianapolis (5)
I believe the answer is:
diana
'she's' is the definition.
'from indianapolis' is the wordplay.
'from' indicates the answer is hidden within the clue.
'DIANA' is hidden within 'indianapolis'.
(Other definitions for diana that I've seen before include "female" , "She separated from Charles" , "Girl's name; goddess" , "Roman equivalent of Artemis" , "Roman huntress goddess" .)