She's made to resist relatively speaking (6)
I believe the answer is:
sister
'speaking' is the definition.
Both the answer and definition are adjectives. Maybe you can see an association between them that I can't see?
'she's made to resist relatively' is the wordplay.
'resist' can be anagrammed to 'SISTER'.
But, I am not clear how the anagram is indicated.
Can you help me to learn more?
(Other definitions for sister that I've seen before include "Relative in hospital?" , "'Nurse, nun or relative (6)'" , "Tender" , "A kinswoman" , "Close relation" .)