Shocked response from one of a pair rankles occasionally (6,4)
I believe the answer is:
double take
'shocked response' is the definition.
'double take' can be an answer for 'response' (double take is a kind of response). I am unsure of the 'shocked' bit.
'one of a pair rankles occasionally' is the wordplay.
'one of a pair' becomes 'doublet' (I am not sure about this - if you are sure you should believe this answer much more).
'occasionally' indicates alternate letters.
The alternate letters of 'rankles' are 'ake'.
'doublet'+'ake'='DOUBLE TAKE'
'from' is the link.
Can you help me to learn more?
(Other definitions for double take that I've seen before include "Delayed action" , "Second reaction to the unexpected" .)