Shoot up, ingesting drink and drug before adult show (4,5)
I believe the answer is:
soap opera
'show' is the definition.
(soap opera is a kind of show)
I don't understand the remainder of the clue.
(Other definitions for soap opera that I've seen before include "Sentimental TV serial, sounds clean" , "addictive programme?" , "that might involve The Woolpack?" , "Serialised domestic melodrama on TV or radio" , "A dramatic broadcast" .)