Show organ pierced by bit of anti-aircraft fire? (10)
I believe the answer is:
blackadder
'show' is the definition.
(TV sitcom)
'organ pierced by bit of anti-aircraft fire?' is the wordplay.
'organ' becomes 'bladder' (I've seen this before).
'pierced by' indicates putting letters inside (inserted letters pierce the word).
'bit of anti-aircraft fire?' becomes 'ack' (ack-ack was WW1 radio slang for aircraft fire).
'bladder' enclosing 'ack' is 'BLACKADDER'.
(Other definitions for blackadder that I've seen before include "Recurrent historical character on TV" , "Cash desk" , "Comedy hero" , "TV show" .)